Cart
sales@molnova.com
Calpeptin
CAS No. 117591-20-5
Calpeptin( Calpeptin | Benzylcarbonyl-leu-nleu-H | N-Cbz-leu-nleu-al. )
Catalog No. M10597 CAS No. 117591-20-5
Calpeptin is a potent, cell-permeable calpain inhibitor with ID50 of 52 nM, 34 nM, 138 nM, and 40 nM for Calpain I (porcine erythrocytes), Calpain II (porcine kidney), Papainb, and Calpain I (human platelets), respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 47 | In Stock |
|
| 10MG | 68 | In Stock |
|
| 25MG | 146 | In Stock |
|
| 50MG | 205 | In Stock |
|
| 100MG | 335 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCalpeptin
-
NoteResearch use only, not for human use.
-
Brief DescriptionCalpeptin is a potent, cell-permeable calpain inhibitor with ID50 of 52 nM, 34 nM, 138 nM, and 40 nM for Calpain I (porcine erythrocytes), Calpain II (porcine kidney), Papainb, and Calpain I (human platelets), respectively.
-
DescriptionCalpeptin is a potent, cell-permeable calpain inhibitor with ID50 of 52 nM, 34 nM, 138 nM, and 40 nM for Calpain I (porcine erythrocytes), Calpain II (porcine kidney), Papainb, and Calpain I (human platelets), respectively.
-
In Vitro——
-
In VivoAnimal Model:C57BL/6 female mice (Eight-week-old).Dosage:0.04 mg/mouse.Administration:Intraperitoneally three times weekly for 28 days (together with Bleo).Result:Inhibited the collagen deposition and increase of calpain activity in the NSC-125066 treated mouse lung tissues.
-
SynonymsCalpeptin | Benzylcarbonyl-leu-nleu-H | N-Cbz-leu-nleu-al.
-
PathwayProteasome/Ubiquitin
-
TargetCysteine Protease
-
RecptorCalpain 1(human platelets)| Calpain 1(porcine erythrocytes)| Calpain 2(porcine kidney)| Papainb
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number117591-20-5
-
Formula Weight362.46
-
Molecular FormulaC20H30N2O4
-
Purity>98% (HPLC)
-
SolubilityDMSO:72 mg/mL (198.64 mM); Ethanol:72 mg/mL (198.64 mM); Water:<1 mg/mL (<1 mM)
-
SMILESO=C(OCC1=CC=CC=C1)N[C@H](C(N[C@H](C=O)CCCC)=O)CC(C)C
-
Chemical Namebenzyl ((S)-4-methyl-1-oxo-1-(((S)-1-oxohexan-2-yl)amino)pentan-2-yl)carbamate
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Tsujinaka T, et al. Biochem Biophys Res Commun. 1988, 153(3), 1201-1208.
molnova catalog
related products
-
Leupeptin Hemisulfat...
Leupeptin Hemisulfate is a reversible inhibitor of serine and cysteine proteases.
-
Dazcapistat
Dazcapistat is a potent calpain inhibitor, with IC50s of <3 μM for calpain 1, calpain 2 and calpain 9, respectively.
-
N-Ethylmaleimide
N-ethylmaleimide is a sulfhydryl reagent that is widely used in experimental biochemical studies.
