CYP11B2-IN-1

CAS No. 1356479-78-1

CYP11B2-IN-1 ( —— )

Catalog No. M26133 CAS No. 1356479-78-1

CYP11B2-IN-1 is a CYP11B2 inhibitor with IC50 of 2.3 nM. CYP11B2-IN-1 inhibits CYP11B1 with IC50 of 142 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 118 Get Quote
5MG 177 Get Quote
10MG 282 Get Quote
25MG 480 Get Quote
50MG 691 Get Quote
100MG 972 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    CYP11B2-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    CYP11B2-IN-1 is a CYP11B2 inhibitor with IC50 of 2.3 nM. CYP11B2-IN-1 inhibits CYP11B1 with IC50 of 142 nM.
  • Description
    CYP11B2-IN-1 is a CYP11B2 inhibitor with IC50 of 2.3 nM. CYP11B2-IN-1 inhibits CYP11B1 with IC50 of 142 nM.(In Vitro):The IC50 of CYP11B2-IN-1 for CYP19 is 1021 nM.(In Vivo):CYP11B2-IN-1 dose-dependently produces aldosterone lowering efficacy without affecting cortisol levels in rhesus pharmacodynamic models. CYP11B2-IN-1 (0.01 and 0.3 mg/kg; i.v.) reduces aldosterone AUC of 62% and 95%, respectively.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1356479-78-1
  • Formula Weight
    311.4
  • Molecular Formula
    C18H18FN3O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C)(O)c1cncc(c1)-c1nc2ccc(F)cc2n1C1CC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.An Y, Zheng H, Yu Z, Sun Y, Wang Y, Zhao C, Ding W. Functioned hollow glass microsphere as a self-floating adsorbent: Rapid and high-efficient removal of anionic dye. J Hazard Mater. 2020 Jan 5;381:120971. doi: 10.1016/j.jhazmat.2019.120971. Epub 2019 Aug 10. PMID: 31421555.
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