CYP11B2-IN-1
CAS No. 1356479-78-1
CYP11B2-IN-1 ( —— )
Catalog No. M26133 CAS No. 1356479-78-1
CYP11B2-IN-1 is a CYP11B2 inhibitor with IC50 of 2.3 nM. CYP11B2-IN-1 inhibits CYP11B1 with IC50 of 142 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 118 | Get Quote |
|
5MG | 177 | Get Quote |
|
10MG | 282 | Get Quote |
|
25MG | 480 | Get Quote |
|
50MG | 691 | Get Quote |
|
100MG | 972 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
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Biological Information
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Product NameCYP11B2-IN-1
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NoteResearch use only, not for human use.
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Brief DescriptionCYP11B2-IN-1 is a CYP11B2 inhibitor with IC50 of 2.3 nM. CYP11B2-IN-1 inhibits CYP11B1 with IC50 of 142 nM.
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DescriptionCYP11B2-IN-1 is a CYP11B2 inhibitor with IC50 of 2.3 nM. CYP11B2-IN-1 inhibits CYP11B1 with IC50 of 142 nM.(In Vitro):The IC50 of CYP11B2-IN-1 for CYP19 is 1021 nM.(In Vivo):CYP11B2-IN-1 dose-dependently produces aldosterone lowering efficacy without affecting cortisol levels in rhesus pharmacodynamic models. CYP11B2-IN-1 (0.01 and 0.3 mg/kg; i.v.) reduces aldosterone AUC of 62% and 95%, respectively.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number1356479-78-1
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Formula Weight311.4
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Molecular FormulaC18H18FN3O
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(C)(O)c1cncc(c1)-c1nc2ccc(F)cc2n1C1CC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.An Y, Zheng H, Yu Z, Sun Y, Wang Y, Zhao C, Ding W. Functioned hollow glass microsphere as a self-floating adsorbent: Rapid and high-efficient removal of anionic dye. J Hazard Mater. 2020 Jan 5;381:120971. doi: 10.1016/j.jhazmat.2019.120971. Epub 2019 Aug 10. PMID: 31421555.
molnova catalog
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