CU-CPT-9a

CAS No. 2165340-32-7

CU-CPT-9a( —— )

Catalog No. M20662 CAS No. 2165340-32-7

CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM) that suppresses TLR8-mediated proinflammatory signaling in various cell lines.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 43 In Stock
5MG 72 In Stock
10MG 115 In Stock
25MG 224 In Stock
50MG 410 In Stock
100MG 605 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    CU-CPT-9a
  • Note
    Research use only, not for human use.
  • Brief Description
    CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM) that suppresses TLR8-mediated proinflammatory signaling in various cell lines.
  • Description
    CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM) that suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    TLR
  • Recptor
    TLR8
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2165340-32-7
  • Formula Weight
    265.31
  • Molecular Formula
    C17H15NO2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:150 mg/mL (565.38 mM)
  • SMILES
    COc1ccc2c(ccnc2c1)-c1ccc(O)c(C)c1
  • Chemical Name
    2-Methyl-4-(7-methoxy-4-quinolinyl)phenol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhang S Hu Z Tanji H et al. Small-molecule inhibition of TLR8 through stabilization of its resting state[J]. Nature Chemical Biology 2017 14(1):58-64.
molnova catalog
related products
  • Tomaralimab

    Tomaralimab (OPN-305) is a humanized IgG4 monoclonal antibody targeting TLR2, used to study myelodysplastic syndromes (MDS).

  • TLR4-IN-C34

    TLR4-IN-C34 is an orally active TLR4 inhibitor and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis.

  • CU-CPT-8m

    CU-CPT-8m is an toll-like receptor 8 (TLR8) antagonist (IC50 : 67 nM).