CRT0044876

CAS No. 6960-45-8

CRT0044876 ( CRT0044876; CRT-0044876; CRT 0044876 )

Catalog No. M19009 CAS No. 6960-45-8

CRT0044876 is a potent and selective APE1 inhibitor with IC50 of ~3 μM.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 34 In Stock
25MG 55 In Stock
50MG 77 In Stock
100MG 97 In Stock
200MG 122 In Stock
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Biological Information

  • Product Name
    CRT0044876
  • Note
    Research use only, not for human use.
  • Brief Description
    CRT0044876 is a potent and selective APE1 inhibitor with IC50 of ~3 μM.
  • Description
    CRT0044876 is a potent BER inhibitor or DNA Base Excision Repair Pathway Inhibitor (APE1 IC50 - 3 microM). CRT0044876 potentiates the cytotoxicity of several DNA base-targeting compounds, with accumulation of apurinic sites.
  • Synonyms
    CRT0044876; CRT-0044876; CRT 0044876
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    APE1
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    6960-45-8
  • Formula Weight
    206.15
  • Molecular Formula
    C9H6N2O4
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    OC(=O)C1=CC2=C(N1)C(=CC=C2)[N+]([O-])=O
  • Chemical Name
    7-Nitro-1H-indole-2-carboxylic acid.

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Madhusudan S, et al. Nucleic Acids Res. 2005, 33(15), 4711-4724.
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