Cart
sales@molnova.com
Home - Products - GPCR/G Protein - Antibacterial - CRS-3123

CRS-3123

CAS No. 1013915-71-3

CRS-3123( CRS3123 | REP 3123 )

Catalog No. M10078 CAS No. 1013915-71-3

A novel diaryldiamine that inhibits bacterial methionyl-tRNA synthetases in Gram-positive bacteria as a novel agent to treat Clostridium difficile infection (CDI).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 1323 Get Quote
50MG 2682 Get Quote
100MG 3600 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    CRS-3123
  • Note
    Research use only, not for human use.
  • Brief Description
    A novel diaryldiamine that inhibits bacterial methionyl-tRNA synthetases in Gram-positive bacteria as a novel agent to treat Clostridium difficile infection (CDI).
  • Description
    A novel diaryldiamine that inhibits bacterial methionyl-tRNA synthetases in Gram-positive bacteria as a novel agent to treat Clostridium difficile infection (CDI); inhibits de novo toxin production in high cell density, stationary phase cultures of C. difficile at 1 mg/L; demonstrates efficacy in the hamster model of CDI and is superior to vancomycin 0.5 mg/kg in CDI model.Bacterial Infection Phase 1 Clinical.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    CRS3123 | REP 3123
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    Infection
  • Indication
    Bacterial Infection

Chemical Information

  • CAS Number
    1013915-71-3
  • Formula Weight
    515.264
  • Molecular Formula
    C19H21Br2N3O2S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (194.84 mM)
  • SMILES
    BrC1=CC(Br)=C2OCC[C@H](C2=C1)NCCCNC3=CC(C4SC=CC4N3)=O
  • Chemical Name
    5-((3-(((R)-6,8-dibromochroman-4-yl)amino)propyl)amino)-3a,7a-dihydrothieno[3,2-b]pyridin-7(4H)-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Citron DM, et al. J Antimicrob Chemother. 2009 May;63(5):972-6. 2. Ochsner UA, et al. J Antimicrob Chemother. 2009 May;63(5):964-71. 3. Critchley IA, et al. J Antimicrob Chemother. 2009 May;63(5):954-63.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • N-(3-cyano-4,5,6,7-t...

    N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)pyrazine-2-carboxamide exhibit an inhibitory effect on bacterial DNA helicases, nucleases, or helicase-nuclease enzyme complexes, such as, for example, one or more enzymes selected from the RecBCD and AddAB families of enzymes.

  • Acetyl alkannin

    Acetyl alkannin is an isohexenylnaphthazarin pigment isolated from Arnebia euchroma, with antimicrobial and cytotoxic activities.

  • MUT-056399

    A novel, highly potent inhibitor of the FabI enzyme of both Staphylococcus aureus and Escherichia coli.

Sign In Join Free