MUT-056399

CAS No. 1269055-85-7

MUT-056399 ( FAB-001 )

Catalog No. M11129 CAS No. 1269055-85-7

A novel, highly potent inhibitor of the FabI enzyme of both Staphylococcus aureus and Escherichia coli.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 177 Get Quote
10MG 295 Get Quote
25MG 498 Get Quote
50MG 710 Get Quote
100MG 963 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    MUT-056399
  • Note
    Research use only, not for human use.
  • Brief Description
    A novel, highly potent inhibitor of the FabI enzyme of both Staphylococcus aureus and Escherichia coli.
  • Description
    A novel, highly potent inhibitor of the FabI enzyme of both Staphylococcus aureus and Escherichia coli; shows activity against S. aureus strains, including MSSA, MRSA, linezolid-resistant, and multidrug-resistant strains with MIC90s of 0.03-0.12 ug/ml; also has active against coagulase-negative staphylococci with MIC90s of 0.12-4 ug/ml; active in vivo (19.3-49.6 mg/kg/day).Bacterial Infection Preclinical
  • Synonyms
    FAB-001
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    Infection
  • Indication
    Bacterial Infection

Chemical Information

  • CAS Number
    1269055-85-7
  • Formula Weight
    293.27
  • Molecular Formula
    C15H13F2NO3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 31 mg/mL
  • SMILES
    CCC1=CC(=C(C=C1F)OC2=C(C=C(C=C2)C(=O)N)F)O
  • Chemical Name
    Benzamide, 4-(4-ethyl-5-fluoro-2-hydroxyphenoxy)-3-fluoro-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Escaich S, et al. Antimicrob Agents Chemother. 2011 Oct;55(10):4692-7.
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