Cart
sales@molnova.com
CMP-5
CAS No. 880813-42-3
CMP-5 ( PRMT5-IN-5 )
Catalog No. M16388 CAS No. 880813-42-3
CMP-5 (PRMT5-IN-5)is a first-in-class, small-molecule PRMT5-specific inhibitor that blocks EBV-driven B-lymphocyte transformation and survival.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameCMP-5
-
NoteResearch use only, not for human use.
-
Brief DescriptionCMP-5 (PRMT5-IN-5)is a first-in-class, small-molecule PRMT5-specific inhibitor that blocks EBV-driven B-lymphocyte transformation and survival.
-
DescriptionCMP-5 (PRMT5-IN-5)is a first-in-class, small-molecule PRMT5-specific inhibitor that blocks EBV-driven B-lymphocyte transformation and survival, without effect on normal B cells; displays no activity against other type I (PRMT1 and PRMT4) and type II (PRMT7) enzymes; inhibition of PRMT5 leads to lost recruitment of a PRMT5/p65/HDAC3-repressive complex on the miR96 promoter, restored miR96 expression, and PRMT5 downregulation.
-
SynonymsPRMT5-IN-5
-
PathwayChromatin/Epigenetic
-
TargetHMTase
-
RecptorHMTase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number880813-42-3
-
Formula Weight315.42
-
Molecular FormulaC21H21N3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCCN1C2=C(C=C(C=C2)CNCC3=CC=CC=N3)C4=CC=CC=C41.Cl
-
Chemical Name1-(9-Ethyl-9H-carbazol-3-yl)-N-(2-pyridinylmethyl)methanamine
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Alinari L, et al. Blood. 2015 Apr 16;125(16):2530-43.
molnova catalog
related products
-
CMP-5
CMP-5 (PRMT5-IN-5)is a first-in-class, small-molecule PRMT5-specific inhibitor that blocks EBV-driven B-lymphocyte transformation and survival.
-
T1551
T1551 is a novel, potent and specific PRMT5 inhibitor with IC50 of 34.1 uM.
-
WDR5-0103
A potent MLL1-WDR5 interaction inhibitor with IC50 of 26.4 nM in competitive binding assay.
