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CL075
CAS No. 256922-53-9
CL075( —— )
Catalog No. M34210 CAS No. 256922-53-9
CL075 (3M002) is a selective TLR8 agonist with immunomodulatory activity, triggering the MyD88-dependent signaling pathway and activating NF-κB and IRF7 to elicit the production of inflammatory cytokines and type I interferon (IFN).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 52 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameCL075
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NoteResearch use only, not for human use.
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Brief DescriptionCL075 (3M002) is a selective TLR8 agonist with immunomodulatory activity, triggering the MyD88-dependent signaling pathway and activating NF-κB and IRF7 to elicit the production of inflammatory cytokines and type I interferon (IFN).
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DescriptionCL075 (3M002) is a selective TLR8 agonist with immunomodulating properties. CL075 triggers a MyD88-dependent signaling pathway to elicit production of inflammatory cytokines and type I interferons (IFNs) via activation of NF-κB and IRF7, respectively.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetNF-κB
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RecptorNF-κB | MyD88 | TLR
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Research Area——
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Indication——
Chemical Information
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CAS Number256922-53-9
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Formula Weight243.33
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Molecular FormulaC13H13N3S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 22 mg/mL (90.41 mM; 超声加热助溶)
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SMILESCCCc1nc2c(N)nc3ccccc3c2s1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lai CY, et, al. TLR7/8 agonists activate a mild immune response in rabbits through TLR8 but not TLR7. Vaccine. 2014 Sep 29;32(43):5593-9.?
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