Cart
sales@molnova.com
Home - Products - Others - Other Targets - CI-976

CI-976

CAS No. 114289-47-3

CI-976( PD 128042 )

Catalog No. M10507 CAS No. 114289-47-3

CI-976 (PD 128042) is a potent, selective, orally bioavailable inhibitor of ACAT-1 (Acetyl-CoA acetyltransferase 1) with IC50 of 73 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 55 Get Quote
5MG 78 Get Quote
10MG 116 Get Quote
25MG 251 Get Quote
50MG 467 Get Quote
100MG 677 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    CI-976
  • Note
    Research use only, not for human use.
  • Brief Description
    CI-976 (PD 128042) is a potent, selective, orally bioavailable inhibitor of ACAT-1 (Acetyl-CoA acetyltransferase 1) with IC50 of 73 nM.
  • Description
    CI-976 (PD 128042) is a potent, selective, orally bioavailable inhibitor of ACAT-1 (Acetyl-CoA acetyltransferase 1) with IC50 of 73 nM; decreases plasma total cholesterol, very low density lipoprotein (VLDL) cholesterol, LDL cholesterol, apolipoprotein B, liver cholesteryl esters, and VLDL and LDL cholesteryl ester content in rabbits.Atherosclerosis Discontinued.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    PD 128042
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Other Targets
  • Research Area
    Cardiovascular Disease
  • Indication
    Atherosclerosis

Chemical Information

  • CAS Number
    114289-47-3
  • Formula Weight
    393.568
  • Molecular Formula
    C23H39NO4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (254.09 mM)
  • SMILES
    CCCCCCCCCCC(C)(C)C(=O)NC1=C(C=C(C=C1OC)OC)OC
  • Chemical Name
    2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)-dodecanamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Field FJ, et al. Lipids. 1991 Jan;26(1):1-8. 2. O'Brien PM, et al. J Med Chem. 1994 Jun 10;37(12):1810-22. 3. Krause BR, et al. J Lipid Res. 1993 Feb;34(2):279-94. 4. Baba T, et al. Mol Cell Biochem. 2013 Apr;376(1-2):151-61.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products
Sign In Join Free