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CI-976
CAS No. 114289-47-3
CI-976 ( PD 128042 )
Catalog No. M10507 CAS No. 114289-47-3
CI-976 (PD 128042) is a potent, selective, orally bioavailable inhibitor of ACAT-1 (Acetyl-CoA acetyltransferase 1) with IC50 of 73 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 55 | Get Quote |
|
| 5MG | 78 | Get Quote |
|
| 10MG | 116 | Get Quote |
|
| 25MG | 251 | Get Quote |
|
| 50MG | 467 | Get Quote |
|
| 100MG | 677 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameCI-976
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NoteResearch use only, not for human use.
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Brief DescriptionCI-976 (PD 128042) is a potent, selective, orally bioavailable inhibitor of ACAT-1 (Acetyl-CoA acetyltransferase 1) with IC50 of 73 nM.
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DescriptionCI-976 (PD 128042) is a potent, selective, orally bioavailable inhibitor of ACAT-1 (Acetyl-CoA acetyltransferase 1) with IC50 of 73 nM; decreases plasma total cholesterol, very low density lipoprotein (VLDL) cholesterol, LDL cholesterol, apolipoprotein B, liver cholesteryl esters, and VLDL and LDL cholesteryl ester content in rabbits.Atherosclerosis Discontinued
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SynonymsPD 128042
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PathwayOthers
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TargetOther Targets
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RecptorOther Targets
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Research AreaCardiovascular Disease
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IndicationAtherosclerosis
Chemical Information
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CAS Number114289-47-3
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Formula Weight393.57
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Molecular FormulaC23H39NO4
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Purity>98% (HPLC)
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Solubility——
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SMILESCCCCCCCCCCC(C)(C)C(=O)NC1=C(C=C(C=C1OC)OC)OC
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Chemical Name2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)-dodecanamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Field FJ, et al. Lipids. 1991 Jan;26(1):1-8.
2. O'Brien PM, et al. J Med Chem. 1994 Jun 10;37(12):1810-22.
3. Krause BR, et al. J Lipid Res. 1993 Feb;34(2):279-94.
4. Baba T, et al. Mol Cell Biochem. 2013 Apr;376(1-2):151-61.
2. O'Brien PM, et al. J Med Chem. 1994 Jun 10;37(12):1810-22.
3. Krause BR, et al. J Lipid Res. 1993 Feb;34(2):279-94.
4. Baba T, et al. Mol Cell Biochem. 2013 Apr;376(1-2):151-61.
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