This is amino acids 86 to 100 fragment of class II-associated invariant chain peptide called CLIP. The major histocompatibility complex class II molecule displays peptide fragments of foreign proteins to trigger a defensive reaction from the immune system. Before insertion of the foreign peptides into the binding groove, a place-holding peptide CLIP is removed. This is accomplished by the molecule DM, which is shown to increase the dissociation rate of a CLIP peptide from class II.

Ianalumab (VAY-736) is a decarboxylated humanized antibody against BAFF-R that inhibits the interaction between BAFF and BAFF-R, blocking BAFF-mediated apoptosis protection.

[D-Pro4,D-Trp7,9,10,Val8]-Substance P (4-11)