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CGP-74514A
CAS No. 190653-73-7
CGP-74514A( CGP 74514A | CGP74514A )
Catalog No. M12989 CAS No. 190653-73-7
A potent, dual CDC-like kinase (CLK)/CDK inhibitor with IC50 of 148, 111, 104, 382 and 573 nM for CLK1, CLK2, CLK4, CDK1 and CDK4, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameCGP-74514A
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, dual CDC-like kinase (CLK)/CDK inhibitor with IC50 of 148, 111, 104, 382 and 573 nM for CLK1, CLK2, CLK4, CDK1 and CDK4, respectively.
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DescriptionA potent, dual CDC-like kinase (CLK)/CDK inhibitor with IC50 of 148, 111, 104, 382 and 573 nM for CLK1, CLK2, CLK4, CDK1 and CDK4, respectively.
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In Vitro——
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In Vivo——
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SynonymsCGP 74514A | CGP74514A
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PathwayCell Cycle/DNA Damage
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TargetCLK
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RecptorCLK
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Research Area——
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Indication——
Chemical Information
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CAS Number190653-73-7
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Formula Weight385.9
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Molecular FormulaC19H24ClN7
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Purity>98% (HPLC)
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Solubility——
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SMILESCCN1C=NC2=C(N=C(N=C21)NC3CCCCC3N)NC4=CC(=CC=C4)Cl
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Chemical NameN2-((1R,2S)-2-aminocyclohexyl)-N6-(3-chlorophenyl)-9-ethyl-9H-purine-2,6-diamine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Shi Y, et al. Bioorg Med Chem Lett. 2017 Feb 1;27(3):406-412.
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