CFI02( CFI 02 | CFI-02 )

Catalog No. M13838 CAS No. 273735-28-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Get Quotation Bulk Inquiry Add to Cart

Product Name

CFI02
Note

Research use only, not for human use.
Brief Description

CFI02 (CFI-02) is a specific inhibitor of human cytomegalovirus (HCMV) glycoprotein B-mediated fusion with IC50 of 40 nM against laboratory adapted HCMV strain AD169.
Description

CFI02 (CFI-02) is a specific inhibitor of human cytomegalovirus (HCMV) glycoprotein B-mediated fusion with IC50 of 40 nM against laboratory adapted HCMV strain AD169; reduces HCMV yield by >3 logs at 1 uM, and shows no inhibitory activity against closely related betaherpesviruses (including MCMV, simian CMV, and RCMV) (IC50>20 uM) as well as cytotoxic effect (CC50>50 uM).
In Vitro

——
In Vivo

——
Synonyms

CFI 02 | CFI-02
Pathway

Microbiology/Virology
Target

CMV
Recptor

CMV
Research Area

——
Indication

——

CAS Number

273735-28-7
Formula Weight

491.43
Molecular Formula

C18H11F6N5OS2
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

N-(4-(3-(3,5-bis(trifluoromethyl)phenyl)thioureido)phenyl)-1,2,3-thiadiazole-4-carboxamide

1. Jones TR, et al. J Virol. 2004 Feb;78(3):1289-300. 2. Bloom JD, et al. Bioorg Med Chem Lett. 2003 Sep 1;13(17):2929-32.

Calculator

molnova catalog