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Home - Products - Metabolic Enzyme/Protease - Phospholipase - CCT129957

CCT129957

CAS No. 883098-58-6

CCT129957( —— )

Catalog No. M33309 CAS No. 883098-58-6

CCT129957 is a novel and potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of about 3 μM and a GC50 of 15 μM.CCT129957 exhibits anticancer activity and inhibits Ca2+ release in squamous cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 59 Get Quote
5MG 85 Get Quote
10MG 128 Get Quote
25MG 225 Get Quote
50MG 338 Get Quote
100MG 497 Get Quote
500MG 1053 Get Quote
1G Get Quote Get Quote
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Biological Information

  • Product Name
    CCT129957
  • Note
    Research use only, not for human use.
  • Brief Description
    CCT129957 is a novel and potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of about 3 μM and a GC50 of 15 μM.CCT129957 exhibits anticancer activity and inhibits Ca2+ release in squamous cells.
  • Description
    CCT129957 is an indole derivative and a potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of ~3 μM and a GC50 of 15 μM. CCT129957 inhibits Ca2+ release in squamous carcinoma cells at ~15 μM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Phospholipase
  • Recptor
    Phospholipase | Calcium Channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    883098-58-6
  • Formula Weight
    309.32
  • Molecular Formula
    C17H15N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (323.29 mM; Ultrasonic )
  • SMILES
    [O-][N+](=O)c1cccc2cc([nH]c12)C(=O)NCCc1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Reynisson J, et al. The identification of novel PLC-gamma inhibitors using virtual high throughput screening. Bioorg Med Chem. 2009 Apr 15;17(8):3169-76.?
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