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IQDMA

CAS No. 401463-02-3

IQDMA( C524250 | IQDMA cpd | IQDMA )

Catalog No. M14373 CAS No. 401463-02-3

A cell-permeable, small molecule inhibitor of the transcription factor STAT5.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    IQDMA
  • Note
    Research use only, not for human use.
  • Brief Description
    A cell-permeable, small molecule inhibitor of the transcription factor STAT5.
  • Description
    A cell-permeable, small molecule inhibitor of the transcription factor STAT5 that exhibits anticancer activity and inhibits the growth of A549, HL-60 and K562 cells with IC50 of 8, 5 and 8 uM, respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    C524250 | IQDMA cpd | IQDMA
  • Pathway
    JAK/STAT Signaling
  • Target
    STAT
  • Recptor
    STAT
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    401463-02-3
  • Formula Weight
    304.397
  • Molecular Formula
    C19H20N4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CN(C)CCNC1=NC2=CC=CC=C2C3=C1C4=C(N3)C=CC=C4
  • Chemical Name
    N'-(11H-indolo[3,2-c]quinolin-6-yl)-N,N-dimethylethane-1,2-diamine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hu XW, et al. Cell Biol Toxicol. 2006 Nov;22(6):417-27. 2. Chien CM, et al. Chem Biol Interact. 2008 Oct 22;176(1):40-7. 3. Hodge LS, et al. Blood. 2014 Feb 13;123(7):1055-8.
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