CAY10505

CAS No. 1218777-13-9

CAY10505 ( CAY10505; CAY 10505; CAY10505 )

Catalog No. M10821 CAS No. 1218777-13-9

CAY10505 is dehydroxyl of AS-252424, which is a PI3Kγ inhibitor with IC50 of 33 nM.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 35 In Stock
25MG 61 In Stock
50MG 105 In Stock
100MG 168 In Stock
200MG 250 In Stock
500MG 428 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    CAY10505
  • Note
    Research use only, not for human use.
  • Brief Description
    CAY10505 is dehydroxyl of AS-252424, which is a PI3Kγ inhibitor with IC50 of 33 nM.
  • Description
    CAY10505 is dehydroxyl of AS-252424, which is a PI3Kγ inhibitor with IC50 of 33 nM.
  • Synonyms
    CAY10505; CAY 10505; CAY10505
  • Pathway
    PI3K/Akt/mTOR signaling
  • Target
    PI3K
  • Recptor
    PI3Kγ
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1218777-13-9
  • Formula Weight
    289.28
  • Molecular Formula
    C14H8FNO3S
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO: 58 mg/mL (200.49 mM)
  • SMILES
    O=C(NC/1=O)SC1=C\C2=CC=C(C3=CC=C(F)C=C3)O2
  • Chemical Name
    (E)-5-((5-(4-fluorophenyl)furan-2-yl)methylene)thiazolidine-2,4-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Tyagi S, Sharma S, Budhiraja RD.Can J Physiol Pharmacol. 2012 Jul;90(7):881-5.
molnova catalog
related products
  • Vps34-IN-1

    Vps34-IN-1 is a potent, selective inhibitor of class III PI3K Vps34 with IC50 of 25 nM.

  • Splitomicin

    Splitomicin (IC50 of 60 μM), a specific inhibitor of NAD(+)-dependent histone deacetylase Sir2p, displays a high activity in a cell-based assay.

  • GNE-317

    GNE-317 (GNE317) is a potent, brain penepenetrant, dual PI3K/mTOR inhibitor having physicochemical properties predictive of low efflux by P-gp and BCRP.