CADD522

CAS No. 199735-88-1

CADD522 ( MFCD00167693 )

Catalog No. M21954 CAS No. 199735-88-1

CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM, with antitumor activityCADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding( IC50 of 10 nM), has antitumor activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 39 Get Quote
10MG 55 Get Quote
25MG 120 Get Quote
50MG 203 Get Quote
100MG 357 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    CADD522
  • Note
    Research use only, not for human use.
  • Brief Description
    CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM, with antitumor activityCADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding( IC50 of 10 nM), has antitumor activity.
  • Description
    CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM, with antitumor activity.CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding( IC50 of 10 nM), has antitumor activity.
  • Synonyms
    MFCD00167693
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    runt-related transcription factor-2 (RUNX2)-DNA
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    199735-88-1
  • Formula Weight
    326.17
  • Molecular Formula
    C15H13Cl2NO3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:245 mg/ml(751.14 mM; Need ultrasonic)
  • SMILES
    OC(=O)C1C2CC(C=C2)C1C(=O)Nc1ccc(Cl)c(Cl)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kim MS, et al. Characterization of CADD522, a small molecule that inhibits RUNX2-DNA binding and exhibits antitumor activity. Oncotarget. 2017 Aug 10;8(41):70916-70940.
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