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CADD522

CAS No. 199735-88-1

CADD522 ( MFCD00167693 )

Catalog No. M21954 CAS No. 199735-88-1

CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM, with antitumor activityCADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding( IC50 of 10 nM), has antitumor activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    CADD522
  • Note
    Research use only, not for human use.
  • Brief Description
    CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM, with antitumor activityCADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding( IC50 of 10 nM), has antitumor activity.
  • Description
    CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding with an IC50 of 10 nM, with antitumor activity.CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA binding( IC50 of 10 nM), has antitumor activity.
  • Synonyms
    MFCD00167693
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    runt-related transcription factor-2 (RUNX2)-DNA
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    199735-88-1
  • Formula Weight
    326.17
  • Molecular Formula
    C15H13Cl2NO3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:245 mg/ml(751.14 mM; Need ultrasonic)
  • SMILES
    OC(=O)C1C2CC(C=C2)C1C(=O)Nc1ccc(Cl)c(Cl)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kim MS, et al. Characterization of CADD522, a small molecule that inhibits RUNX2-DNA binding and exhibits antitumor activity. Oncotarget. 2017 Aug 10;8(41):70916-70940.
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