6-NBDG

CAS No. 108708-22-1

6-NBDG( —— )

Catalog No. M35804 CAS No. 108708-22-1

6-NBDG, a fluorescent glucose analogue, can be used as a fluorescent probe.6-NBDG can be used for monitoring glucose transport and uptake. 6-NBDG can be used as for detecting macrophage-rich atherosclerotic plaques.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    6-NBDG
  • Note
    Research use only, not for human use.
  • Brief Description
    6-NBDG, a fluorescent glucose analogue, can be used as a fluorescent probe.6-NBDG can be used for monitoring glucose transport and uptake. 6-NBDG can be used as for detecting macrophage-rich atherosclerotic plaques.
  • Description
    6-NBDG is a fluorescent glucose analogue, it can be used for fluorescence imaging and monitoring glucose transport and uptake. 6-NBDG can be used as a fluorescent probe for detecting macrophage-rich atherosclerotic plaques.
  • In Vitro
    Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs).1. Incubate sample with RPMI (without glucose) containing a final concentration of 200 μM 6-NBDG.2. Use a curved forcep to embeds sample into the mixture, and stretches the samplet through a drop of agarose (40°C, 20 μL) places on a pre-heated (40°C) glass slide.3. Gently place another preheated glass slide on the top of sample, so that the whole sample embeds into the agarose-6-NBDG mixture.4. Take confocal images with a confocal laser scanning microscope (Ex: 471 nm, Em: 500–600 nm).
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    108708-22-1
  • Formula Weight
    342.26
  • Molecular Formula
    C12H14N4O8
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 10 mg/mL (29.22 mM)
  • SMILES
    O=[N+]([O-])C1=CC=C(NC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O)C2=NON=C21
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hansen TV, et al. Glucose Absorption by the Bacillary Band of Trichuris muris. PLoS Negl Trop Dis. 2016 Sep 2;10(9):e0004971. ?
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