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Busulfan
CAS No. 55-98-1
Busulfan( Busulphan | Mielosan | Milecitan | Myeloleukon | Mylecytan | Myleran | NCI C01592 | NSC 750 )
Catalog No. M15037 CAS No. 55-98-1
Busulfan is a bifunctional alkylating agent.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 41 | In Stock |
|
| 1G | 56 | In Stock |
|
Biological Information
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Product NameBusulfan
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NoteResearch use only, not for human use.
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Brief DescriptionBusulfan is a bifunctional alkylating agent.
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DescriptionBusulfan is a bifunctional alkylating agent.
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In VitroWestern Blot Analysis Cell Line:WI38 cells Concentration:120 μM Incubation Time:24 hours Result:Incited a moderate p53 activation, but strong Erk, p38, and JNK phosphorylation, in a time-dependent manner. Elicited an immediate up-regulation of p21 expression, which subsided by day 11.
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In VivoAnimal Model:ICR male mice ranging in age from 8 to 12 weeks (30-40 g) Dosage:40 mg/kg (in sesame oil) Administration:IP; single dose Result:Increased apoptosis and decreased the testis weight in mice. Exhibited higher level of pRB expression, inhibited Rb phosphorylation and PCNA expression compared to the control.
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SynonymsBusulphan | Mielosan | Milecitan | Myeloleukon | Mylecytan | Myleran | NCI C01592 | NSC 750
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PathwayCell Cycle/DNA Damage
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TargetDNA Alkylator
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RecptorDNA Alkylation
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number55-98-1
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Formula Weight246.3
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Molecular FormulaC6H14O6S2
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Purity>98% (HPLC)
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SolubilityDMSO: 49 mg/mL (198.94 mM)
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SMILESCS(=O)(OCCCCOS(C)(=O)=O)=O
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Chemical Namebutane-1,4-diyl dimethanesulfonate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Meng A, et al. Y Res, 2003, 63(17), 5414-5419.
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