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Bromelain

CAS No. 9001-00-7

Bromelain( —— )

Catalog No. M26076 CAS No. 9001-00-7

Bromelain is an anti-inflammatory drug derived from pineapple stem.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Bromelain
  • Note
    Research use only, not for human use.
  • Brief Description
    Bromelain is an anti-inflammatory drug derived from pineapple stem.
  • Description
    Bromelain is an anti-inflammatory drug derived from pineapple stem. It acts through down-regulation of plasma kininogen, degradation of advanced glycation end-product receptors, inhibition of Prostaglandin E2 expression, and regulation of angiogenic biomarkers as well as antioxidant action upstream in the COX-pathway.(In Vivo):Bromelain (40 mg/kg; i.p.; daily; for 7 days; male SD rats) pretreatment reduces the motor dysfunction in the parkinsonian rat model of Parkinson's disease. 6-OHDA injection resulted in a marked motor impairment which is prevented by pretreatment with Bromelain prior to the lesion .
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male Sprague-Dawley rats injected with 6-OHDA Dosage:40 mg/kg Administration:Intraperitoneal injection; daily; for 7 days Result:Reduced the motor dysfunction in the parkinsonian rat model of parkinson's disease (PD).
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    9001-00-7
  • Formula Weight
    ——
  • Molecular Formula
    ——
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 6.67 mg/mL
  • SMILES
    CC1OC(OC2C(NC(C)=O)C(O)OC(CO)C2OC2OC(CO)C(OC3OC(COC4OC(CO)C(O)C(O)C4O)C(O)C(O)C3OC3OCC(O)C(O)C3O)C(O)C2NC(C)=O)C(O)C(O)C1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wang C C , Tolman R L , Simashkevich P M , et al. Arprinocid, an inhibitor of hypoxanthine- guanine transport[J]. Biochemical Pharmacology, 1979, 28(15):2249-2260.
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