
Bromelain
CAS No. 9001-00-7
Bromelain( —— )
Catalog No. M26076 CAS No. 9001-00-7
Bromelain is an anti-inflammatory drug derived from pineapple stem.
Purity : >98% (HPLC)






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Biological Information
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Product NameBromelain
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NoteResearch use only, not for human use.
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Brief DescriptionBromelain is an anti-inflammatory drug derived from pineapple stem.
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DescriptionBromelain is an anti-inflammatory drug derived from pineapple stem. It acts through down-regulation of plasma kininogen, degradation of advanced glycation end-product receptors, inhibition of Prostaglandin E2 expression, and regulation of angiogenic biomarkers as well as antioxidant action upstream in the COX-pathway.(In Vivo):Bromelain (40 mg/kg; i.p.; daily; for 7 days; male SD rats) pretreatment reduces the motor dysfunction in the parkinsonian rat model of Parkinson's disease. 6-OHDA injection resulted in a marked motor impairment which is prevented by pretreatment with Bromelain prior to the lesion .
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In Vitro——
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In VivoAnimal Model:Male Sprague-Dawley rats injected with 6-OHDA Dosage:40 mg/kg Administration:Intraperitoneal injection; daily; for 7 days Result:Reduced the motor dysfunction in the parkinsonian rat model of parkinson's disease (PD).
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Synonyms——
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PathwayApoptosis
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TargetApoptosis
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number9001-00-7
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Formula Weight——
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Molecular Formula——
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 6.67 mg/mL
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SMILESCC1OC(OC2C(NC(C)=O)C(O)OC(CO)C2OC2OC(CO)C(OC3OC(COC4OC(CO)C(O)C(O)C4O)C(O)C(O)C3OC3OCC(O)C(O)C3O)C(O)C2NC(C)=O)C(O)C(O)C1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Wang C C , Tolman R L , Simashkevich P M , et al. Arprinocid, an inhibitor of hypoxanthine- guanine transport[J]. Biochemical Pharmacology, 1979, 28(15):2249-2260.
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