Cart
sales@molnova.com
Boc-Val-Cit-PAB-PNP
CAS No. 870487-10-8
Boc-Val-Cit-PAB-PNP ( —— )
Catalog No. M22613 CAS No. 870487-10-8
Boc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 35 | In Stock |
|
| 10MG | 57 | In Stock |
|
| 25MG | 85 | In Stock |
|
| 50MG | 120 | In Stock |
|
| 100MG | 173 | In Stock |
|
| 500MG | 434 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameBoc-Val-Cit-PAB-PNP
-
NoteResearch use only, not for human use.
-
Brief DescriptionBoc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
-
DescriptionBoc-Val-Cit-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
-
Synonyms——
-
PathwayPROTACs
-
TargetPROTAC
-
RecptorCleavable
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number870487-10-8
-
Formula Weight644.67
-
Molecular FormulaC30H40N6O10
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCC(C)[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)Oc2ccc(cc2)[N+]([O-])=O)cc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
molnova catalog
related products
-
BTK PROTAC 9
BTK PROTAC 9 is a novel potent PROTAC for BTK with DC50 of 5.9 nM in cultured Ramos cells.
-
MZ 1
MZ 1 is a PROTAC BRD4 degrader. MZ 1 potently and rapidly induces reversible, long-lasting, and selective removal of BRD4 over BRD2 and BRD3. Kds of 382/120, 119/115, and 307/228 nM for BRD4 BD1/2, BRD3 BD1/2, and BRD2 BD1/2, respectively.
-
Amino-PEG11-amine
Amino-PEG11-amine, a PEG-based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer.
