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Boc-NH-PEG4-CH2COOH

CAS No. 876345-13-0

Boc-NH-PEG4-CH2COOH( —— )

Catalog No. M24891 CAS No. 876345-13-0

Boc-NH-PEG4-CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Boc-NH-PEG4-CH2COOH
  • Note
    Research use only, not for human use.
  • Brief Description
    Boc-NH-PEG4-CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC).
  • Description
    Boc-NH-PEG4-CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC).
  • In Vitro
    ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Antibody Drug Conjugates (ADC)
  • Target
    ADCs Linker/Click Chemistry
  • Recptor
    Cleavable
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    876345-13-0
  • Formula Weight
    351.39
  • Molecular Formula
    C15H29NO8
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(O)COCCOCCOCCOCCNC(OC(C)(C)C)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Maggie Lu, et al. Linker-drug and antibody-drug conjugate (adc) employing the same. EP3335734A1.
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