m-PEG8-Ms

Research use only, not for human use.

m-PEG8-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

m-PEG8-Ms is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG8-Ms is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

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Antibody Drug Conjugates (ADC)

ADCs Linker/Click Chemistry

ADC Linker

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1059588-19-0

462.55

C18H38O11S

>98% (HPLC)

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O=S(=O)(OCCOCCOCCOCCOCCOCCOCCOCCOC)C

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(-20℃)

With Ice Pack

≥ 2 years