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Boc-NH-PEG3-CH2COOH

CAS No. 462100-06-7

Boc-NH-PEG3-CH2COOH( —— )

Catalog No. M24415 CAS No. 462100-06-7

Boc-NH-PEG3-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Boc-NH-PEG3-CH2COOH
  • Note
    Research use only, not for human use.
  • Brief Description
    Boc-NH-PEG3-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC
  • Description
    Boc-NH-PEG3-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    PROTACs
  • Target
    PROTAC
  • Recptor
    PEGs|Alkyl/ether
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    462100-06-7
  • Formula Weight
    307.34
  • Molecular Formula
    C13H25NO7
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (325.37 mM)
  • SMILES
    O=C(OC(C)(C)C)NCCOCCOCCOCC(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Vollmer S, et al. Design, Synthesis, and Biological Evaluation of MEK PROTACs. J Med Chem. 2020 Jan 9;63(1):157-162.
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