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Boc-C14-COOH
CAS No. 843666-27-3
Boc-C14-COOH( —— )
Catalog No. M28899 CAS No. 843666-27-3
Boc-C14-COOH is a alkyl-chain-based PROTAC linker. Boc-C14-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 29 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameBoc-C14-COOH
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NoteResearch use only, not for human use.
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Brief DescriptionBoc-C14-COOH is a alkyl-chain-based PROTAC linker. Boc-C14-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DescriptionBoc-C14-COOH is a alkyl-chain-based PROTAC linker. Boc-C14-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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In VitroADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorMuscarinic AChR
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Research Area——
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Indication——
Chemical Information
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CAS Number843666-27-3
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Formula Weight341.513
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Molecular FormulaC20H37O4
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(C)(C)OC(=O)CCCCCCCCCCCCCCC([O-])=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Jiménez-Rosés M, et al. Ligand-Triggered Structural Changes in the M(2) Muscarinic Acetylcholine Receptor. J Chem Inf Model. 2018 May 29;58(5):1074-1082.
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