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Blebbistatin

CAS No. 674289-55-5

Blebbistatin ( (±)-Blebbistatin )

Catalog No. M24685 CAS No. 674289-55-5

Blebbistatin is a selective non-muscle myosin II (NMII) inhibitor. It promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 63 In Stock
10MG 120 In Stock
25MG 203 In Stock
50MG 357 In Stock
100MG 538 In Stock
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Biological Information

  • Product Name
    Blebbistatin
  • Note
    Research use only, not for human use.
  • Brief Description
    Blebbistatin is a selective non-muscle myosin II (NMII) inhibitor. It promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing.
  • Description
    Blebbistatin is a selective non-muscle myosin II (NMII) inhibitor. It promotes directional migration of corneal endothelial cells (CECs) and accelerates wound healing. Furthermore it preserves cell junctional integrity and barrier function.
  • Synonyms
    (±)-Blebbistatin
  • Pathway
    Endocrinology/Hormones
  • Target
    ATPase
  • Recptor
    non-muscle myosin II ATPases
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    674289-55-5
  • Formula Weight
    292.3
  • Molecular Formula
    C18H16N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 23 mg/mL (78.67 mM; Need ultrasonic)
  • SMILES
    Cc(cc1)cc(C(C2(CC3)O)=O)c1N=C2N3c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ho WT, et al. Targeting non-muscle myosin II promotes corneal endothelial migration through regulating lamellipodial dynamics. J Mol Med (Berl). 2019 Sep;97(9):1345-1357.
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