Bitertanol

CAS No. 55179-31-2

Bitertanol ( Biloxazol; Baycor; Sibutol; KWG 0599; KWG0599; KWG-0599; )

Catalog No. M27857 CAS No. 55179-31-2

Bitertanol is a triazole fungicide. Bitertanol inhibits demethylation, disrupts membrane function, and prevents sterol synthesis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 45 Get Quote
10MG 63 Get Quote
25MG 103 Get Quote
50MG 150 Get Quote
100MG 223 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Bitertanol
  • Note
    Research use only, not for human use.
  • Brief Description
    Bitertanol is a triazole fungicide. Bitertanol inhibits demethylation, disrupts membrane function, and prevents sterol synthesis.
  • Description
    Bitertanol is a triazole fungicide. Bitertanol inhibits demethylation, disrupts membrane function, and prevents sterol synthesis.(In Vivo):Bitertanol (10, 25, and 100 mg/kg) produced 2-, 4-, and 14-fold increases of 7-ethoxyresorufin O-deethylation activity in liver microsomes, respectively. Bitertanol (25 mg/kg) increased CYP1A1 protein in the liver, kidney, and lung by 10-, 13-, and 17-fold, respectively. Bitertanol produced smaller increases of CYP2B and CYP3A catalytic activity and protein than that of CYP1A1 in liver. Additions of 0.01-100 microM Bitertanol to liver microsomes from rats Bitertanol (25 mg/kg) inhibited microsomal 7-ethoxyresorufin O-demethylation activity (IC50=0.8 microM). Bitertanol (100 mg/kg) increased liver UDP-glucuronosyltransferase and glutathione S-transferase activities by 2-fold. Bitertanol (25 mg/kg) produced a minor increase in metabolic activation of benzo[a]pyrene by liver S-9 fraction in the Ames mutagenicity test while the increase was blocked by addition of 100 microM Bitertanol.
  • Synonyms
    Biloxazol; Baycor; Sibutol; KWG 0599; KWG0599; KWG-0599;
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    55179-31-2
  • Formula Weight
    337.4
  • Molecular Formula
    C20H23N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C)(C)C(O)C(Oc1ccc(cc1)-c1ccccc1)n1cncn1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Liu, Jing; Plewe, Michael Bruno; Wang, Jialiang; Han, Xiaoran; Chen, Liqun. Preparation of pyrazolopyridines and related heterocycles as CBP and p300 degradation bivalent compds for treatment of diseases.
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