Bisdemethoxycurcumin
CAS No. 24939-16-0
Bisdemethoxycurcumin ( Curcumin III, Bisdemethoxycurcumin )
Catalog No. M18307 CAS No. 24939-16-0
Bisdemethoxycurcumin (BDMC) is a natural demethoxy derivative of curcumin.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 37 | In Stock |
|
50MG | 122 | In Stock |
|
100MG | 183 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameBisdemethoxycurcumin
-
NoteResearch use only, not for human use.
-
Brief DescriptionBisdemethoxycurcumin (BDMC) is a natural demethoxy derivative of curcumin.
-
DescriptionBisdemethoxycurcumin (BDMC) is a natural demethoxy derivative of curcumin. It is a potent activator of macrophage phagocytosis, interacting with 1α, 25-dihydroxy vitamin D3 to stimulate amyloid-β clearance by macrophages (optimal stimulation at 100 nM BDMC) [1]. More stable than curcumin in physiological media, BDMC suppresses proliferation of cancer cells. It down-regulates the transcriptional coactivator p300, suppressing the Wnt/β-catenin pathway, and inhibits LPS induction of iNOS expression.
-
SynonymsCurcumin III, Bisdemethoxycurcumin
-
PathwayOthers
-
TargetOther Targets
-
Recptorp300;Wnt/β-catenin
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number24939-16-0
-
Formula Weight308.33
-
Molecular FormulaC19H16O4
-
Purity98%
-
Solubility——
-
SMILESOc2ccc(/C=C/C(=O)CC(=O)/C=C/c1ccc(O)cc1)cc2
-
Chemical Name(1E,6E)-1,7-Bis(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Fiala, M., Liu, P.T., Espinosa-Jeffrey, A., et al. Proceedings of the National Academy of Sciences of the United States of America 104(31), 12849-12854 (2007).
molnova catalog
related products
-
Cyanidin-3-O-arabino...
Cyanidin-3-O-arabinoside chloride has antioxidant activity. It reduces the peroxynitrite-induced suppression of mitochondrial respiration, DNA damage, PARS activation and vascular dysfunction in HUVECs.
-
Terpinyl Acetate
Terpinyl Acetate is a natural compound found in several essential oils is a flavouring agent.
-
Germanaism C
The herbs of Iris germanica.