Bisantrene
CAS No. 78186-34-2
Bisantrene ( CL216942 )
Catalog No. M15949 CAS No. 78186-34-2
A small molecule DNA intercalater with antineoplastic activity, does not exhibit cardiotoxicity compared with doxorubicin; induces both protein-associated DNA single-strand breaks and DNA-protein crosslinks in cancer cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 31 | In Stock |
|
10MG | 41 | In Stock |
|
25MG | 91 | In Stock |
|
50MG | 152 | In Stock |
|
100MG | 255 | In Stock |
|
200MG | 434 | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameBisantrene
-
NoteResearch use only, not for human use.
-
Brief DescriptionA small molecule DNA intercalater with antineoplastic activity, does not exhibit cardiotoxicity compared with doxorubicin; induces both protein-associated DNA single-strand breaks and DNA-protein crosslinks in cancer cells.
-
DescriptionA small molecule DNA intercalater with antineoplastic activity, does not exhibit cardiotoxicity compared with doxorubicin; induces both protein-associated DNA single-strand breaks and DNA-protein crosslinks in cancer cells.
-
SynonymsCL216942
-
PathwayCell Cycle/DNA Damage
-
TargetDNA Alkylator
-
RecptorTopoisomerase;topoisomerases
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number78186-34-2
-
Formula Weight398.46
-
Molecular FormulaC22H22N8
-
Purity>98% (HPLC)
-
SolubilityDMSO: ≥ 133.33 mg/mL
-
SMILESC1CN=C(N1)NN=CC2=C3C=CC=CC3=C(C4=CC=CC=C42)C=NNC5=NCCN5
-
Chemical Name9,10-Anthracenedicarboxaldehyde, 9,10-bis[(4,5-dihydro-1H-imidazol-2-yl)hydrazone]
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Citarella RV, et al. Cancer Res. 1982 Feb;42(2):440-4.
2. Von Hoff DD, et al. Cancer Chemother Pharmacol. 1981;6(2):141-4.
3. Von Hoff DD, et al. Cancer Res. 1982 Feb;42(2):440-4.
4. Lown JW, et al. Mol Pharmacol. 1984 Jan;25(1):178-84.
2. Von Hoff DD, et al. Cancer Chemother Pharmacol. 1981;6(2):141-4.
3. Von Hoff DD, et al. Cancer Res. 1982 Feb;42(2):440-4.
4. Lown JW, et al. Mol Pharmacol. 1984 Jan;25(1):178-84.
molnova catalog
related products
-
Melphalan
A chemotherapy agent that acts through alkylation of the DNA nucleotide guanine, and causes linkages between strands of DNA; inhibits DNA synthesis and RNA synthesis in both dividing and non-dividing tumor cells.
-
Cisplatin
A chemotherapy agent that interferes with DNA replication and kills cancer cells; induces growth arrest and/or apoptosis in most cancer cell types; an alkylating agent for treatment of a number of cancers.
-
Streptozocin
Streptozotocin is a DNA alkylating agent that enters cells exclusively via the GLUT2 glucose transport protein.