Bisantrene

CAS No. 78186-34-2

Bisantrene ( CL216942 )

Catalog No. M15949 CAS No. 78186-34-2

A small molecule DNA intercalater with antineoplastic activity, does not exhibit cardiotoxicity compared with doxorubicin; induces both protein-associated DNA single-strand breaks and DNA-protein crosslinks in cancer cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 31 In Stock
10MG 41 In Stock
25MG 91 In Stock
50MG 152 In Stock
100MG 255 In Stock
200MG 434 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Bisantrene
  • Note
    Research use only, not for human use.
  • Brief Description
    A small molecule DNA intercalater with antineoplastic activity, does not exhibit cardiotoxicity compared with doxorubicin; induces both protein-associated DNA single-strand breaks and DNA-protein crosslinks in cancer cells.
  • Description
    A small molecule DNA intercalater with antineoplastic activity, does not exhibit cardiotoxicity compared with doxorubicin; induces both protein-associated DNA single-strand breaks and DNA-protein crosslinks in cancer cells.
  • Synonyms
    CL216942
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA Alkylator
  • Recptor
    Topoisomerase;topoisomerases
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    78186-34-2
  • Formula Weight
    398.46
  • Molecular Formula
    C22H22N8
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 133.33 mg/mL
  • SMILES
    C1CN=C(N1)NN=CC2=C3C=CC=CC3=C(C4=CC=CC=C42)C=NNC5=NCCN5
  • Chemical Name
    9,10-Anthracenedicarboxaldehyde, 9,10-bis[(4,5-dihydro-1H-imidazol-2-yl)hydrazone]

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Citarella RV, et al. Cancer Res. 1982 Feb;42(2):440-4.
2. Von Hoff DD, et al. Cancer Chemother Pharmacol. 1981;6(2):141-4.
3. Von Hoff DD, et al. Cancer Res. 1982 Feb;42(2):440-4.
4. Lown JW, et al. Mol Pharmacol. 1984 Jan;25(1):178-84.
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