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Bisantrene

CAS No. 78186-34-2

Bisantrene ( CL216942 )

Catalog No. M15949 CAS No. 78186-34-2

A small molecule DNA intercalater with antineoplastic activity, does not exhibit cardiotoxicity compared with doxorubicin; induces both protein-associated DNA single-strand breaks and DNA-protein crosslinks in cancer cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 31 In Stock
10MG 41 In Stock
25MG 91 In Stock
50MG 152 In Stock
100MG 255 In Stock
200MG 434 In Stock
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Biological Information

  • Product Name
    Bisantrene
  • Note
    Research use only, not for human use.
  • Brief Description
    A small molecule DNA intercalater with antineoplastic activity, does not exhibit cardiotoxicity compared with doxorubicin; induces both protein-associated DNA single-strand breaks and DNA-protein crosslinks in cancer cells.
  • Description
    A small molecule DNA intercalater with antineoplastic activity, does not exhibit cardiotoxicity compared with doxorubicin; induces both protein-associated DNA single-strand breaks and DNA-protein crosslinks in cancer cells.
  • Synonyms
    CL216942
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA Alkylator
  • Recptor
    Topoisomerase;topoisomerases
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    78186-34-2
  • Formula Weight
    398.46
  • Molecular Formula
    C22H22N8
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 133.33 mg/mL
  • SMILES
    C1CN=C(N1)NN=CC2=C3C=CC=CC3=C(C4=CC=CC=C42)C=NNC5=NCCN5
  • Chemical Name
    9,10-Anthracenedicarboxaldehyde, 9,10-bis[(4,5-dihydro-1H-imidazol-2-yl)hydrazone]

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Citarella RV, et al. Cancer Res. 1982 Feb;42(2):440-4.
2. Von Hoff DD, et al. Cancer Chemother Pharmacol. 1981;6(2):141-4.
3. Von Hoff DD, et al. Cancer Res. 1982 Feb;42(2):440-4.
4. Lown JW, et al. Mol Pharmacol. 1984 Jan;25(1):178-84.
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