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Biotin-ONP

CAS No. 33755-53-2

Biotin-ONP( (+)-Biotin 4-nitrophenyl ester )

Catalog No. M27001 CAS No. 33755-53-2

(+)-Biotin-ONP is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Biotin-ONP
  • Note
    Research use only, not for human use.
  • Brief Description
    (+)-Biotin-ONP is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
  • Description
    (+)-Biotin-ONP is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    (+)-Biotin 4-nitrophenyl ester
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    HDAC1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    33755-53-2
  • Formula Weight
    365.4
  • Molecular Formula
    C16H19N3O5S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    [H][C@]12CS[C@@H](CCCCC(=O)Oc3ccc(cc3)[N+]([O-])=O)[C@@]1([H])NC(=O)N2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Patnaik D, et al. Exifone Is a Potent HDAC1 Activator with Neuroprotective Activity in Human Neuronal Models of Neurodegeneration. ACS Chem Neurosci. 2021 Jan 20;12(2):271-284.
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