Biotin-ONP
CAS No. 33755-53-2
Biotin-ONP ( (+)-Biotin 4-nitrophenyl ester )
Catalog No. M27001 CAS No. 33755-53-2
(+)-Biotin-ONP is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
100MG | 43 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameBiotin-ONP
-
NoteResearch use only, not for human use.
-
Brief Description(+)-Biotin-ONP is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
-
Description(+)-Biotin-ONP is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
-
Synonyms(+)-Biotin 4-nitrophenyl ester
-
PathwayOthers
-
TargetOther Targets
-
RecptorHDAC1
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number33755-53-2
-
Formula Weight365.4
-
Molecular FormulaC16H19N3O5S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES[H][C@]12CS[C@@H](CCCCC(=O)Oc3ccc(cc3)[N+]([O-])=O)[C@@]1([H])NC(=O)N2
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Patnaik D, et al. Exifone Is a Potent HDAC1 Activator with Neuroprotective Activity in Human Neuronal Models of Neurodegeneration. ACS Chem Neurosci. 2021 Jan 20;12(2):271-284.
molnova catalog
related products
-
Fmoc-Ala-Ala-Asn(Trt...
Fmoc-Ala-Ala-Asn(Trt)-OH is a cleavable ADC linker used for the antibody-drug conjugates(ADCs).
-
Hydroumbellic acid
Hydroumbellic acid is a predicted metabolite generated by BioTransformer1 that is produced by the metabolism of 3-(2, 4-dihydroxyphenyl)prop-2-enoic acid.
-
Netilmicin sulfate
Netilmicin Sulfate is a member of the aminoglycoside family of antibiotics.