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Bidisomide

CAS No. 116078-65-0

Bidisomide( —— )

Catalog No. M33120 CAS No. 116078-65-0

Bidisomide (SC40230) is an agent of class I antiarrhythmic.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Bidisomide
  • Note
    Research use only, not for human use.
  • Brief Description
    Bidisomide (SC40230) is an agent of class I antiarrhythmic.
  • Description
    Bidisomide (SC40230) is a class I antiarrhythmic agent.
  • In Vitro
    ——
  • In Vivo
    The antiarrhythmic effects of Bidisomide, a new class I antiarrhythmic drug is investigated in early-phase ventricular arrhythmias induced by coronary artery occlusion and reperfusion in anesthetized rats. Bidisomide (5 mg/kg) reduces the number of premature ventricular complexes and the incidence of ventricular tachycardia and ventricular fibrillation similarly to Mexiletine (MXT) and Disopyramide (DSP) in rats with ventricular arrhythmias induced by coronary artery occlusion. In rats with ventricular arrhythmias induced by coronary artery reperfusion following a 5 min coronary occlusion, the antiarrhythmic effects of 5 mg/kg of Bidisomide are similar to those of the same doses of MXT and DSP. All three drugs significantly slow the heart rate.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    116078-65-0
  • Formula Weight
    407.98
  • Molecular Formula
    C22H34ClN3O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (612.78 mM; Ultrasonic )
  • SMILES
    CC(C)N(CCC(CCN1CCCCC1)(C(N)=O)c1ccccc1Cl)C(C)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Komori S, et al. Effects of bidisomide (SC-40230), a new class I antiarrhythmic agent, on ventricular arrhythmias induced by coronary artery occlusion and reperfusion in anesthetized rats; comparison with mexiletine and disopyramide. Heart Vessels. 1995;1?
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