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Besifovir

CAS No. 441785-26-8

Besifovir ( PMCDG Dipivoxil;ANA-380;LB-80380 )

Catalog No. M14501 CAS No. 441785-26-8

Besifovir (PMCDG Dipivoxil, NA-380, LB-80380) is a potent, selective, orally available anti-HBV agent, the prodrug of PMCDG (EC50=4 uM).

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Besifovir
  • Note
    Research use only, not for human use.
  • Brief Description
    Besifovir (PMCDG Dipivoxil, NA-380, LB-80380) is a potent, selective, orally available anti-HBV agent, the prodrug of PMCDG (EC50=4 uM).
  • Description
    Besifovir (PMCDG Dipivoxil, NA-380, LB-80380) is a potent, selective, orally available anti-HBV agent, the prodrug of PMCDG (EC50=4 uM).HBV Infection Phase 3 Clinical
  • Synonyms
    PMCDG Dipivoxil;ANA-380;LB-80380
  • Pathway
    Microbiology/Virology
  • Target
    HBV
  • Recptor
    HBV
  • Research Area
    Infection
  • Indication
    HBV Infection

Chemical Information

  • CAS Number
    441785-26-8
  • Formula Weight
    527.52
  • Molecular Formula
    C22H34N5O8P
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C)(C)C(=O)OCOP(=O)(COC1(CC1)CN2C=NC3=CN=C(N=C32)N)OCOC(=O)C(C)(C)C
  • Chemical Name
    [[1-[(2-aminopurin-9-yl)methyl]cyclopropyl]oxymethyl-(2,2-dimethylpropanoyloxymethoxy)phosphoryl]oxymethyl 2,2-dimethylpropanoate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Choi JR, et al. J Med Chem. 2004 May 20;47(11):2864-9.
2. Yuen MF, et al. Hepatology. 2010 Mar;51(3):767-76.
3. Papatheodoridis GV, et al. Curr Opin Mol Ther. 2006 Aug;8(4):352-7.
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