AT-406, an orally active antagonist of multiple inhibitor of apoptosis proteins(IAP).

2,2'-Bipyridine is a unique bioactive natural product molecular scaffold commonly used in the core structure of many chelating ligands.

(R)-Nepicastat HCl, the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors.