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Benzyl-PEG12-alcohol
CAS No. 2218463-17-1
Benzyl-PEG12-alcohol( —— )
Catalog No. M35140 CAS No. 2218463-17-1
Benzyl-PEG12-alcohol is a PEG-based linker for PROTACs, connecting two essential ligands to form PROTAC molecules. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 76 | Get Quote |
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| 5MG | 55 | Get Quote |
|
| 10MG | 81 | Get Quote |
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| 25MG | 118 | Get Quote |
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| 50MG | 164 | Get Quote |
|
| 100MG | 232 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameBenzyl-PEG12-alcohol
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NoteResearch use only, not for human use.
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Brief DescriptionBenzyl-PEG12-alcohol is a PEG-based linker for PROTACs, connecting two essential ligands to form PROTAC molecules. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.
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DescriptionBenzyl-PEG12-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorPROTACs
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Research Area——
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Indication——
Chemical Information
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CAS Number2218463-17-1
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Formula Weight636.77
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Molecular FormulaC31H56O13
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Purity>98% (HPLC)
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Solubility——
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SMILESOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC=1C=CC=CC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562?
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