
Benzotript
CAS No. 39544-74-6
Benzotript( —— )
Catalog No. M22224 CAS No. 39544-74-6
Benzotript is an gastrin-receptor antagonist, with anti-gastrinic.proglumide and benzotript, a new tryptophan derivative, to inhibit acid output from isolated gastric fundic parietal cells from rabbit.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
2MG | 178 | In Stock |
![]() ![]() |
5MG | 268 | In Stock |
![]() ![]() |
10MG | 408 | In Stock |
![]() ![]() |
25MG | 672 | In Stock |
![]() ![]() |
50MG | 945 | In Stock |
![]() ![]() |
100MG | 1278 | In Stock |
![]() ![]() |
200MG | Get Quote | In Stock |
![]() ![]() |
500MG | Get Quote | In Stock |
![]() ![]() |
1G | Get Quote | In Stock |
![]() ![]() |
Biological Information
-
Product NameBenzotript
-
NoteResearch use only, not for human use.
-
Brief DescriptionBenzotript is an gastrin-receptor antagonist, with anti-gastrinic.proglumide and benzotript, a new tryptophan derivative, to inhibit acid output from isolated gastric fundic parietal cells from rabbit.
-
DescriptionBenzotript is an gastrin-receptor antagonist, with anti-gastrinic.proglumide and benzotript, a new tryptophan derivative, to inhibit acid output from isolated gastric fundic parietal cells from rabbit.?As measured with the [14C]aminopyrine (AP) accumulation method as an index of acid secretion, the two drugs inhibited basal AP with IC-50 values of 1 X 10(-2) M for proglumide and 1 X 10(-3) M for benzotript.?In the case of secretagogue stimulation (1) benzotript slightly affected histamine-induced AP (15% inhibition at 5 X 10(-3) M), proglumide did not;?(2) both proglumide and benzotript inhibited in a non-competitive manner acetylcholine-induced AP;?(3) these isolated cells were sensitive to gastrin and the dose-response curve for the stimulant was biphasic (maximum for 1 X 10(-9) M), suggesting a desensitization mechanism.?Proglumide and benzotript competitively inhibited both [125I]gastrin binding to its receptor sites and gastrin-induced AP, suggesting they are members of a class of gastrin-receptor antagonists.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
Recptorgastrin-receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number39544-74-6
-
Formula Weight342.78
-
Molecular FormulaC18H15ClN2O3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(O)[C@H](CC1=CNC2=C1C=CC=C2)NC(C3=CC=C(Cl)C=C3)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Magous R , Bali J P . Evidence that proglumide and benzotript antagonize secretagogue stimulation of isolated gastric parietal cells.[J]. Regulatory Peptides, 1983, 7(3):233-241.
molnova catalog



related products
-
Rabies Virus Glycopr...
Rabies Virus Glycoprotein (TFA) is a kind of by the Rabies Virus Glycoprotein 29 - amino acid derived cell penetrating peptides, it can pass the blood brain barrier (BBB) into the brain cells.
-
Giganteone C
The herbs of Curcuma wenyujin Y.H.Chen & C.Ling.
-
6-Diazo-5-oxo-L-nor-...
6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine) is a glutaminase antagonist (Ki: 6 μM) and an antineoplastic antibiotic produced by an unidentified Streptomyces species from Peruvian soil.