Benorilate

CAS No. 5003-48-5

Benorilate( Benorilate | Win-11450 | Win 11450 | Win11450 | TO125 | Salipran | Fenasparate )

Catalog No. M14678 CAS No. 5003-48-5

Benorylate (Benoral) is the esterification product of paracetamol and acetylsalicylic acid. It has anti-inflammatory, analgesic and antipyretic properties. Benorylate could also inhibit prostaglandin (PG) synthesis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Benorilate
  • Note
    Research use only, not for human use.
  • Brief Description
    Benorylate (Benoral) is the esterification product of paracetamol and acetylsalicylic acid. It has anti-inflammatory, analgesic and antipyretic properties. Benorylate could also inhibit prostaglandin (PG) synthesis.
  • Description
    Benorylate (Benoral) is the esterification product of paracetamol and acetylsalicylic acid. It has anti-inflammatory, analgesic and antipyretic properties. Benorylate could also inhibit prostaglandin (PG) synthesis.(In Vitro):Benorylate (Salipran) is an esterified aspirin preparation whose antirheumatic properties are reported to be as good as those of aspirin.Benorylate (Salipran) causes a large decrease in the liver’s conversion rate of lactate into glucose, an important component of glucose homeostasis. Benorylate (Salipran) also impairs the urea synthesis rate from ammonia, another important function of the liver.(In Vivo):Benorylate (Salipran) is probably absorbed as the intact molecule which accounts for its good gastric tolerance.Benorylate (Salipran) could inhibit PG synthesis in laboratory animals and in human tissue.
  • In Vitro
    Benorylate (Salipran) is an esterified aspirin preparation whose antirheumatic properties are reported to be as good as those of aspirin.Benorylate (Salipran) causes a large decrease in the liver’s conversion rate of lactate into glucose, an important component of glucose homeostasis. Benorylate (Salipran) also impairs the urea synthesis rate from ammonia, another important function of the liver.
  • In Vivo
    Benorylate (Salipran) is probably absorbed as the intact molecule which accounts for its good gastric tolerance. Benorylate (Salipran) could inhibit PG synthesis in laboratory animals and in human tissue.
  • Synonyms
    Benorilate | Win-11450 | Win 11450 | Win11450 | TO125 | Salipran | Fenasparate
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    5003-48-5
  • Formula Weight
    313.3
  • Molecular Formula
    C17H15NO5
  • Purity
    >98% (HPLC)
  • Solubility
    Soluble in DMSO
  • SMILES
    O=C(OC1=CC=C(NC(C)=O)C=C1)C2=CC=CC=C2OC(C)=O
  • Chemical Name
    4-acetamidophenyl 2-acetoxybenzoate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Simila S et al. Eur J Pediatr. 1975 Dec 9;121(1):15-20.
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