Cart
sales@molnova.com
Home - Products - Cell Cycle/DNA Damage - HDAC - Belinostat

Belinostat

CAS No. 414864-00-9

Belinostat ( PXD101 )

Catalog No. M14420 CAS No. 414864-00-9

Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity.

Purity : >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 35 In Stock
10MG 56 In Stock
25MG 88 In Stock
50MG 132 In Stock
100MG 195 In Stock
200MG 312 In Stock
500MG 520 In Stock
1G Get Quote In Stock
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Belinostat
  • Note
    Research use only, not for human use.
  • Brief Description
    Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity.
  • Description
    Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase.
  • Synonyms
    PXD101
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    414864-00-9
  • Formula Weight
    318.35
  • Molecular Formula
    C15H14N2O4S
  • Purity
    >98%(HPLC)
  • Solubility
    DMSO: 64 mg/mL (201.03 mM)
  • SMILES
    C1=CC=C(C=C1)NS(=O)(=O)C2=CC=CC(=C2)/C=C/C(=O)NO
  • Chemical Name
    2-Propenamide, N-hydroxy-3-(3-((phenylamino)sulfonyl)phenyl)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Savickiene J, et al. anticancer Drugs. 2014 Sep;25(8):938-49.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Vorinostat

    A potent HDAC inhibitor, inhibits the activities of HDAC1 and HDAC3 with IC50 of 10 nM and 20 nM, respectively.

  • Sodium Phenylbutyrat...

    Sodium Phenylbutyrate is a transcriptional regulators that act by altering chromatin structure via the modulation of HDAC activity.

  • Valproic acid

    A HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2.

Sign In Join Free