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Batabulin

CAS No. 195533-53-0

Batabulin ( T138067 )

Catalog No. M23886 CAS No. 195533-53-0

Batabulin is an antitumor compound, which binds covalently and selectively to a subset of the β-tubulin isotypes, thereby disrupting microtubule polymerization.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Batabulin
  • Note
    Research use only, not for human use.
  • Brief Description
    Batabulin is an antitumor compound, which binds covalently and selectively to a subset of the β-tubulin isotypes, thereby disrupting microtubule polymerization.
  • Description
    Batabulin is an antitumor compound, which binds covalently and selectively to a subset of the β-tubulin isotypes, thereby disrupting microtubule polymerization. Batabulin affects cell morphology and leads to cell-cycle arrest ultimately induce apoptotic cell death.
  • Synonyms
    T138067
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis;Tubulin β
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    195533-53-0
  • Formula Weight
    371.3
  • Molecular Formula
    C13H7F6NO3S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL (269.35 mM; Need ultrasonic)
  • SMILES
    O=S(C1=C(F)C(F)=C(F)C(F)=C1F)(NC2=CC=C(OC)C(F)=C2)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Shan B, et al. Selective, covalent modification of beta-tubulin residue Cys-239 by T138067, an antitumor agent with in vivo efficacy against multidrug-resistant tumors. Proc Natl Acad Sci U S A. 1999 May 11;96(10):5686-91.
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