
Batabulin
CAS No. 195533-53-0
Batabulin( T138067 )
Catalog No. M23886 CAS No. 195533-53-0
Batabulin is an antitumor compound, which binds covalently and selectively to a subset of the β-tubulin isotypes, thereby disrupting microtubule polymerization.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
5MG | 110 | In Stock |
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10MG | 160 | In Stock |
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25MG | 282 | In Stock |
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50MG | 417 | In Stock |
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100MG | 601 | In Stock |
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500MG | 1242 | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NameBatabulin
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NoteResearch use only, not for human use.
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Brief DescriptionBatabulin is an antitumor compound, which binds covalently and selectively to a subset of the β-tubulin isotypes, thereby disrupting microtubule polymerization.
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DescriptionBatabulin is an antitumor compound, which binds covalently and selectively to a subset of the β-tubulin isotypes, thereby disrupting microtubule polymerization. Batabulin affects cell morphology and leads to cell-cycle arrest ultimately induce apoptotic cell death.
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In VitroCell Cycle Analysis Cell Line:MCF7 cells Concentration:30 nM, 100 nM and 300 nM Incubation Time:24 hours Result:Showed an arrest at the G2/M cell-cycle boundary.Apoptosis Analysis Cell Line:MCF7 cells Concentration:30 nM, 100 nM and 300 nM Incubation Time:24 hours or 48 hours Result:25-30% of cells showed the reduced DNA content characteristic of apoptotic cells.
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In VivoAnimal Model:Male athymic nude mice (nu/nu) (6-8 week-old, 20-25 g) injected with CCRF-CEM cells Dosage:40 mg/kg Administration:Intraperitoneal injection; once per week; on days 5, 12, and 19 Result:Impaired the growth of the drug-sensitive CCRF-CEM tumors.
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SynonymsT138067
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PathwayApoptosis
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TargetApoptosis
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RecptorApoptosis|Tubulin β
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Research Area——
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Indication——
Chemical Information
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CAS Number195533-53-0
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Formula Weight371.26
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Molecular FormulaC13H7F6NO3S
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Purity>98% (HPLC)
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SolubilityDMSO:100 mg/mL (269.35 mM; Need ultrasonic)
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SMILESO=S(C1=C(F)C(F)=C(F)C(F)=C1F)(NC2=CC=C(OC)C(F)=C2)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference



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