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BYL-719
CAS No. 1217486-61-7
BYL-719 ( Alpelisib )
Catalog No. M10815 CAS No. 1217486-61-7
Alpelisib (BYL-719) is a potent and selective PI3Kα inhibitor with IC50 of 5 nM in a cell-free assay, and minimal effect on PI3Kβ/γ/δ. Phase 2.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 45 | In Stock |
|
| 10MG | 59 | In Stock |
|
| 25MG | 71 | In Stock |
|
| 50MG | 87 | In Stock |
|
| 100MG | 140 | In Stock |
|
| 200MG | 251 | In Stock |
|
| 500MG | 424 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBYL-719
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NoteResearch use only, not for human use.
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Brief DescriptionAlpelisib (BYL-719) is a potent and selective PI3Kα inhibitor with IC50 of 5 nM in a cell-free assay, and minimal effect on PI3Kβ/γ/δ. Phase 2.
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DescriptionAlpelisib (BYL-719) is a potent and selective PI3Kα inhibitor with IC50 of 5 nM in a cell-free assay, and minimal effect on PI3Kβ/γ/δ. Phase 2.
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SynonymsAlpelisib
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PathwayPI3K/Akt/mTOR signaling
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TargetPI3K
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RecptorPI3Kα
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1217486-61-7
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Formula Weight441.47
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Molecular FormulaC19H22F3N5O2S
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Purity>98%(HPLC)
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SolubilityEthanol: 2 mg/mL (4.53 mM); DMSO: 88 mg/mL (199.33 mM)
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SMILESO=C(N1[C@H](C(N)=O)CCC1)NC2=NC(C)=C(C3=CC(C(C)(C)C(F)(F)F)=NC=C3)S2
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Chemical Name(S)-N1-(4-methyl-5-(2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl)thiazol-2-yl)pyrrolidine-1,2-dicarboxamide.
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Dejan Juric, et al. 2012, AACR 103rd Annual Meeting. Abst CT-0
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