Cart
sales@molnova.com
BRD50837
CAS No. 1314295-24-3
BRD50837( BRD 50837 )
Catalog No. M11264 CAS No. 1314295-24-3
BRD50837 is a potent, selective, small-molecule inhibitor of the Sonic Hedgehog (Shh) pathway with EC50 of 90 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1413 | Get Quote |
|
| 50MG | 2862 | Get Quote |
|
| 100MG | 3870 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameBRD50837
-
NoteResearch use only, not for human use.
-
Brief DescriptionBRD50837 is a potent, selective, small-molecule inhibitor of the Sonic Hedgehog (Shh) pathway with EC50 of 90 nM.
-
DescriptionBRD50837 is a potent, selective, small-molecule inhibitor of the Sonic Hedgehog (Shh) pathway with EC50 of 90 nM, partially lowers Gli1 expression at concentrations of 2 uM, a useful probe of Shh signaling pathway.
-
In Vitro——
-
In Vivo——
-
SynonymsBRD 50837
-
PathwayGPCR/G Protein
-
TargetHedgehog (Hh)
-
RecptorHedgehog (Hh)
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1314295-24-3
-
Formula Weight550.067
-
Molecular FormulaC26H32ClN3O6S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCN(S(=O)(C1=CC=C(Cl)C=C1)=O)C[C@H]2[C@H](CN(C(C3=CC=CC(NC(C4CC4)=O)=C3O2)=O)[C@@H](CO)C)C
-
Chemical NameN-((2R,3S)-2-(((4-chloro-N-methylphenyl)sulfonamido)methyl)-5-((R)-1-hydroxypropan-2-yl)-3-methyl-6-oxo-3,4,5,6-tetrahydro-2H-benzo[b][1,5]oxazocin-10-yl)cyclopropanecarboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Schaefer GI, et al. J Am Chem Soc. 2013 Jul 3;135(26):9675-80.
molnova catalog
related products
-
Robotnikinin
Robotnikinin is asmall molecule that binds the extracellular Sonic Hedgehog (Shh) protein (Kd=3.1 uM) and blocks Shh-signaling in cell lines.
-
Smoothened Agonist (...
SAG is a potent Smoothened (Smo) receptor agonist (Kd = 59 nM).
-
SAG dihydrochloride
SAG dihydrochloride, a powerful agonist of the Smoothened (Smo) receptor (EC 50 = 3 nM; Kd = 59 nM), effectively activates the Hedgehog signaling pathway.
