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BPN14770

CAS No. 1606974-33-7

BPN14770( —— )

Catalog No. M23705 CAS No. 1606974-33-7

BPN14770 is an allosteric inhibitor of selective phosphodiesterase 4D (PDE4D; IC50s: 7.8 nM and 7.4 nM for PDE4D7 and PDE4D3).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    BPN14770
  • Note
    Research use only, not for human use.
  • Brief Description
    BPN14770 is an allosteric inhibitor of selective phosphodiesterase 4D (PDE4D; IC50s: 7.8 nM and 7.4 nM for PDE4D7 and PDE4D3).
  • Description
    BPN14770 is an allosteric inhibitor of selective phosphodiesterase 4D (PDE4D; IC50s: 7.8 nM and 7.4 nM for PDE4D7 and PDE4D3).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    PDE4D3|PDE4D7
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1606974-33-7
  • Formula Weight
    405.8
  • Molecular Formula
    C21H15ClF3NO2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:260 mg/mL (640.71 mM; Need ultrasonic)
  • SMILES
    OC(Cc1ccc(Cc2cc(-c3cccc(Cl)c3)nc(C(F)(F)F)c2)cc1)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ricciarelli R, et al. Memory-enhancing effects of GEBR-32a, a new PDE4D inhibitor holding promise for the treatment of Alzheimer's disease. Sci Rep. 2017 Apr 12;7:46320.
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