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BNC105

CAS No. 945771-74-4

BNC105( —— )

Catalog No. M24994 CAS No. 945771-74-4

BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    BNC105
  • Note
    Research use only, not for human use.
  • Brief Description
    BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.
  • Description
    BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Microtubule/Tubulin
  • Recptor
    tubulin polymerization
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    945771-74-4
  • Formula Weight
    372.37
  • Molecular Formula
    C20H20O7
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:25 mg/mL (67.14 mM; Need ultrasonic);H2O:< 0.1 mg/mL (insoluble)
  • SMILES
    Cc1c(C(c(cc2OC)cc(OC)c2OC)=O)c(ccc(OC)c2O)c2o1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Flynn BL, et al. Discovery of 7-hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan (BNC105), a tubulin polymerization inhibitor with potent antiproliferative and tumor vascular disrupting properties. J Med Chem. 2011 Sep 8;54(17):6014-27.
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