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BMS-986001
CAS No. 634907-30-5
BMS-986001 ( BMS 986001;Censavudine;Festinavir;OBP-601;4'-Ed4T )
Catalog No. M15398 CAS No. 634907-30-5
A thymidine analogue nucleoside reverse transcriptase inhibitor (NRTI) that inhibits HIV-2 isolates from treatment-naive individuals with EC50 of 30-81 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 464 | Get Quote |
|
| 50MG | 2295 | Get Quote |
|
| 100MG | 3591 | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameBMS-986001
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NoteResearch use only, not for human use.
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Brief DescriptionA thymidine analogue nucleoside reverse transcriptase inhibitor (NRTI) that inhibits HIV-2 isolates from treatment-naive individuals with EC50 of 30-81 nM.
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DescriptionA thymidine analogue nucleoside reverse transcriptase inhibitor (NRTI) that inhibits HIV-2 isolates from treatment-naive individuals with EC50 of 30-81 nM; inhibits isolates of HIV-1 with EC50 of 450-890 nM, also exhibits full activity against HIV-2 variants whose genomes encoded the single amino acid changes K65R and Q151M in reverse transcriptase.HIV Infection Phase 2 Clinical
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SynonymsBMS 986001;Censavudine;Festinavir;OBP-601;4'-Ed4T
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIV
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Research AreaInfection
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IndicationHIV Infection
Chemical Information
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CAS Number634907-30-5
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Formula Weight248.24
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Molecular FormulaC12H12N2O4
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C1NC(C(C)=CN1[C@@H]2O[C@@](CO)(C#C)C=C2)=O
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Chemical Name1-[(2R,5R)-5-ethynyl-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Li Z, et al. Antimicrob Agents Chemother. 2013 Nov;57(11):5500-8.
2. Wang F, et al. Antimicrob Agents Chemother. 2013 Dec;57(12):6205-12.
3. Smith RA, et al. Antimicrob Agents Chemother. 2015 Dec;59(12):7437-46.
4. Gupta SK, et al. Lancet HIV. 2016 Jan;3(1):e13-22.
2. Wang F, et al. Antimicrob Agents Chemother. 2013 Dec;57(12):6205-12.
3. Smith RA, et al. Antimicrob Agents Chemother. 2015 Dec;59(12):7437-46.
4. Gupta SK, et al. Lancet HIV. 2016 Jan;3(1):e13-22.
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