Cart
sales@molnova.com
BMS-986001
CAS No. 634907-30-5
BMS-986001 ( BMS 986001;Censavudine;Festinavir;OBP-601;4'-Ed4T )
Catalog No. M15398 CAS No. 634907-30-5
A thymidine analogue nucleoside reverse transcriptase inhibitor (NRTI) that inhibits HIV-2 isolates from treatment-naive individuals with EC50 of 30-81 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 464 | Get Quote |
|
| 50MG | 2295 | Get Quote |
|
| 100MG | 3591 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameBMS-986001
-
NoteResearch use only, not for human use.
-
Brief DescriptionA thymidine analogue nucleoside reverse transcriptase inhibitor (NRTI) that inhibits HIV-2 isolates from treatment-naive individuals with EC50 of 30-81 nM.
-
DescriptionA thymidine analogue nucleoside reverse transcriptase inhibitor (NRTI) that inhibits HIV-2 isolates from treatment-naive individuals with EC50 of 30-81 nM; inhibits isolates of HIV-1 with EC50 of 450-890 nM, also exhibits full activity against HIV-2 variants whose genomes encoded the single amino acid changes K65R and Q151M in reverse transcriptase.HIV Infection Phase 2 Clinical
-
SynonymsBMS 986001;Censavudine;Festinavir;OBP-601;4'-Ed4T
-
PathwayMicrobiology/Virology
-
TargetHIV
-
RecptorHIV
-
Research AreaInfection
-
IndicationHIV Infection
Chemical Information
-
CAS Number634907-30-5
-
Formula Weight248.24
-
Molecular FormulaC12H12N2O4
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C1NC(C(C)=CN1[C@@H]2O[C@@](CO)(C#C)C=C2)=O
-
Chemical Name1-[(2R,5R)-5-ethynyl-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Li Z, et al. Antimicrob Agents Chemother. 2013 Nov;57(11):5500-8.
2. Wang F, et al. Antimicrob Agents Chemother. 2013 Dec;57(12):6205-12.
3. Smith RA, et al. Antimicrob Agents Chemother. 2015 Dec;59(12):7437-46.
4. Gupta SK, et al. Lancet HIV. 2016 Jan;3(1):e13-22.
2. Wang F, et al. Antimicrob Agents Chemother. 2013 Dec;57(12):6205-12.
3. Smith RA, et al. Antimicrob Agents Chemother. 2015 Dec;59(12):7437-46.
4. Gupta SK, et al. Lancet HIV. 2016 Jan;3(1):e13-22.
molnova catalog
related products
-
10-Hydroxy-2-decenoi...
10-Hydroxy-2-decenoic acid is an inhibitor of VEGF-induced angiogenesis, cell migration and proliferation.
-
GSK-8999
GSK-8999 (GSK-2578999) is a novel, potent HIV-1 maturation inhibitor.
-
ZBMA-1
ZBMA-1 is a potent HIV-1 replication inhibitor (IC50=1.01 uM) that efficiently protects APOBEC3G protein by targeting Vif-APOBEC3G complex.
