BMS-303141

CAS No. 943962-47-8

BMS-303141 ( BMS303141; BMS-303141; BMS 303141 )

Catalog No. M17681 CAS No. 943962-47-8

BMS-303141 is a potent ATP-citrate lyase (ACL) inhibitor (IC50: 0.13 uM, human recombinant ACL).

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 35 In Stock
5MG 55 In Stock
10MG 71 In Stock
25MG 129 In Stock
50MG 254 In Stock
100MG 399 In Stock
500MG 893 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    BMS-303141
  • Note
    Research use only, not for human use.
  • Brief Description
    BMS-303141 is a potent ATP-citrate lyase (ACL) inhibitor (IC50: 0.13 uM, human recombinant ACL).
  • Description
    BMS303141 is a potent inhibitor of ATP citrate lyase (ACL). BMS-303141 inhibits lipid synthesis in HepG2 cells with an IC50 of 8 μM, and lowers plasma triglycerides in a murine hyperlipdemia model.
  • Synonyms
    BMS303141; BMS-303141; BMS 303141
  • Pathway
    Endocrinology/Hormones
  • Target
    AChR
  • Recptor
    ACL
  • Research Area
    Metabolic Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    943962-47-8
  • Formula Weight
    424.3
  • Molecular Formula
    C19H15Cl2NO4S
  • Purity
    98%
  • Solubility
    DMSO : ≥ 47 mg/mL; 110.77 mM
  • SMILES
    c1c(cccc1)c1cc(c(cc1)OC)NS(=O)(=O)c1c(O)c(cc(c1)Cl)Cl
  • Chemical Name
    3,5-Dichloro-2-hydroxy-N-(4-methoxy[1,1′-biphenyl]-3-yl)-benzenesulfonamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Li JJ, et al. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3208-11.
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