(-)-(S)-B-973B

CAS No. 2244989-34-0

(-)-(S)-B-973B ( —— )

Catalog No. M24024 CAS No. 2244989-34-0

(-)-(S)-B-973B is an effective allosteric agonist and a positive allosteric modulator of α7 nAChR.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 67 In Stock
5MG 110 In Stock
10MG 176 In Stock
25MG 394 In Stock
50MG 593 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    (-)-(S)-B-973B
  • Note
    Research use only, not for human use.
  • Brief Description
    (-)-(S)-B-973B is an effective allosteric agonist and a positive allosteric modulator of α7 nAChR.
  • Description
    (-)-(S)-B-973B is an effective allosteric agonist and a positive allosteric modulator of α7 nAChR.
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    AChR
  • Recptor
    α7 nAChR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2244989-34-0
  • Formula Weight
    452.5
  • Molecular Formula
    C24H26F2N6O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:65 mg/mL (138.33 mM; Need ultrasonic)
  • SMILES
    C[C@@H](c1nc(N(CC2)CCN2c2ncccc2)cnc1)NC(CCc(cc1)cc(F)c1F)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Garai S, et al. B-973, a Novel α7 nAChR Ago-PAM: Racemic and Asymmetric Synthesis, Electrophysiological Studies, and in Vivo Evaluation. ACS Med Chem Lett. 2018 Oct 11;9(11):1144-1148.
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