BMS-191095
CAS No. 166095-21-2
BMS-191095( —— )
Catalog No. M23744 CAS No. 166095-21-2
BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 237 | In Stock |
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| 10MG | 335 | In Stock |
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| 25MG | 566 | In Stock |
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| 50MG | 806 | In Stock |
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| 100MG | 1098 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBMS-191095
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NoteResearch use only, not for human use.
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Brief DescriptionBMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.
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DescriptionBMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.
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In Vitro——
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In VivoAnimal Model:Male Wistar rats with the induction of ischemia induced by middle cerebral artery occlusion (MCAO)Dosage:2.5 or 25 μg Administration:Intraventricular infusion; 30 min/60 min/24 hours before the induction of ischemia, once Result:Reduced total infarct volume in rats with of pretreat dose of 25 mg and 24 h before MCA. Induced a rapid mitochondrial depolarization.
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetPotassium Channel
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RecptorPotassium Channel
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Research Area——
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Indication——
Chemical Information
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CAS Number166095-21-2
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Formula Weight408.88
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Molecular FormulaC22H21ClN4O2
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Purity>98% (HPLC)
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SolubilityDMSO:90 mg/mL (220.11 mM)
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SMILESCC(C)([C@@H]([C@H]1N(Cc2ncc[nH]2)c(cc2)ccc2Cl)O)Oc(cc2)c1cc2C#N
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Katakam PV, et al. Diversity of mitochondria-dependent dilator mechanisms in vascular smooth muscle of cerebral arteries from normal and insulin-resistant rats. Am J Physiol Heart Circ Physiol. 2014 Aug 15;307(4):H493-503.
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