Dofetilide ( Tikosyn; UK 68789 )

Catalog No. M10538 CAS No. 115256-11-6

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Product Name

Dofetilide
Note

Research use only, not for human use.
Brief Description

Dofetilide is a selective potassium channel ((hERG)) blocker, used as a Class III antiarrhythmic drug
Description

Dofetilide is a selective potassium channel ((hERG)) blocker, used as a Class III antiarrhythmic drug.
Synonyms

Tikosyn; UK 68789
Pathway

Cell Cycle/DNA Damage
Target

Potassium Channel
Recptor

Potassium Channel
Research Area

Cardiovascular Disease
Indication

——

CAS Number

115256-11-6
Formula Weight

441.56
Molecular Formula

C19H27N3O5S2
Purity

>98%(HPLC)
Solubility

DMSO:88 mg/mL warmed (199.29 mM); Ethanol:<1 mg/mL (<1 mM); Water:<1 mg/mL (<1 mM)
SMILES

CS(=O)(NC1=CC=C(OCCN(CCC2=CC=C(NS(=O)(C)=O)C=C2)C)C=C1)=O
Chemical Name

N-(4-(2-(methyl(2-(4-(methylsulfonamido)phenoxy)ethyl)amino)ethyl)phenyl)methanesulfonamide

1. Kiehn J, et al. Circulation, 1996, 94(10), 2572-2579.

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