BM-635( BM635 )

Catalog No. M10301 CAS No. 1073372-01-6

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

BM-635
Note

Research use only, not for human use.
Brief Description

BM-635 is a small molecule anti-mycobacterial compound acting by inhibiting the mycobacterial membrane protein Large 3 (MmpL3).
Description

BM-635 is a small molecule anti-mycobacterial compound acting by inhibiting the mycobacterial membrane protein Large 3 (MmpL3); shows outstanding anti-mycobacterial activity (MIC of 0.12 uM against M. tuberculosis H37Rv).
In Vitro

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In Vivo

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Synonyms

BM635
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Antibacterial
Research Area

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Indication

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CAS Number

1073372-01-6
Formula Weight

331.223
Molecular Formula

C17H26BN3O3
Purity

>98% (HPLC)
Solubility

——
SMILES

B1(OC(C(O1)(C)C)(C)C)C2=CN=C(C=C2)N3CCN(CC3)C(=O)C
Chemical Name

1-[4-[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]-1-piperazinyl]ethanone

1. Poce G, et al. Eur J Pharm Sci. 2017 Mar 1;99:17-23. 2. Poce G, et al. Eur J Med Chem. 2017 Dec 27;145:539-550.

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