BIO-7662 ( BIO 7662;BIO7662 )

Catalog No. M14064 CAS No. 327613-10-5

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

BIO-7662
Note

Research use only, not for human use.
Brief Description

A potent, highly selective α4β1 integrin antagonist with Kd of <10 pM.
Description

A potent, highly selective α4β1 integrin antagonist with Kd of <10 pM; the rate of BIO7662 binding is dependent on the metal ion concentration; directly competes with VCAM-1, CS-1, and BIO1211 for binding to the integrin.
Synonyms

BIO 7662;BIO7662
Pathway

Cell Cycle/DNA Damage
Target

Integrin
Recptor

Integrin
Research Area

——
Indication

——

CAS Number

327613-10-5
Formula Weight

748.90
Molecular Formula

C38H48N6O8S
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C(O)[C@@H](NC([C@H]1N(S(=O)(C2=CC=CC=C2)=O)CCC1)=O)CCNC([C@@H](N(C)C(CC3=CC=C(NC(NC4=CC=CC=C4C)=O)C=C3)=O)CC(C)C)=O
Chemical Name

(S)-4-((S)-4-methyl-2-(N-methyl-2-(4-(3-(o-tolyl)ureido)phenyl)acetamido)pentanamido)-2-((S)-1-(phenylsulfonyl)pyrrolidine-2-carboxamido)butanoic acid

1. Chen LL, et al. J Biol Chem. 2001 Sep 28;276(39):36520-9.
2. Egger LA, et al. J Pharmacol Exp Ther. 2003 Sep;306(3):903-13.

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