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BI-D1870
CAS No. 501437-28-1
BI-D1870( BID1870 | BI D1870 | BI-D1870. )
Catalog No. M14686 CAS No. 501437-28-1
BI-D1870 is an ATP-competitive inhibitor of S6 ribosome for RSK1/2/3/4 with IC50 of 31 nM/24 nM/18 nM/15 nM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 125 | In Stock |
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| 10MG | 195 | In Stock |
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| 25MG | 318 | In Stock |
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| 50MG | 447 | In Stock |
|
| 100MG | 624 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBI-D1870
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NoteResearch use only, not for human use.
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Brief DescriptionBI-D1870 is an ATP-competitive inhibitor of S6 ribosome for RSK1/2/3/4 with IC50 of 31 nM/24 nM/18 nM/15 nM, respectively.
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DescriptionBI-D1870 is an ATP-competitive inhibitor of S6 ribosome for RSK1/2/3/4 with IC50 of 31 nM/24 nM/18 nM/15 nM, respectively; 10- to 100-fold selectivity for RSK than MST2, GSK-3β, MARK3, CK1 and Aurora B.
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In Vitro——
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In Vivo——
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SynonymsBID1870 | BI D1870 | BI-D1870.
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PathwayPI3K/Akt/mTOR signaling
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TargetS6 Kinase
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RecptorRSK1| RSK2| RSK3| RSK4
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number501437-28-1
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Formula Weight391.42
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Molecular FormulaC19H23F2N5O2
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Purity>98% (HPLC)
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SolubilityDMSO:78 mg/mL (199.27 mM); Ethanol:<1 mg/mL (<1 mM); Water:<1 mg/mL (<1 mM)
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SMILESO=C1N(C)C2=CN=C(NC3=CC(F)=C(O)C(F)=C3)N=C2N(CCC(C)C)C1C
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Chemical Name2-((3,5-difluoro-4-hydroxyphenyl)amino)-8-isopentyl-5,7-dimethyl-7,8-dihydropteridin-6(5H)-one.
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.GP Sapkota, et al. Biochem J, 2007, 401(Pt 1), 29–38.
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