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BI-7273
CAS No. 1883429-21-7
BI-7273 ( BI7273;BI 7273 )
Catalog No. M12926 CAS No. 1883429-21-7
A potent, selective and cell-permeable BRD9 bromodomain inhibitor with IC50 of 19 nM in Alpha assay.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 58 | In Stock |
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| 5MG | 87 | In Stock |
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| 10MG | 168 | In Stock |
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| 25MG | 339 | In Stock |
|
| 50MG | 537 | In Stock |
|
| 100MG | 764 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBI-7273
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective and cell-permeable BRD9 bromodomain inhibitor with IC50 of 19 nM in Alpha assay.
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DescriptionA potent, selective and cell-permeable BRD9 bromodomain inhibitor with IC50 of 19 nM in Alpha assay; displays >5-fold selectiveity over BRD7, and >5,000-fold over BRD4-BD1, BRD4-BD2, and BRD2-BD1; blocks EOL-1 cell proliferation with EC50 of 1.4 uM, and displays antitumor activity in an AML xenograft model.
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SynonymsBI7273;BI 7273
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PathwayChromatin/Epigenetic
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TargetBromodomain
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RecptorBRD7;BRD9
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1883429-21-7
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Formula Weight353.41
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Molecular FormulaC20H23N3O3
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mg/mL
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SMILESO=C1N(C)C=C(C2=CC(OC)=C(CN(C)C)C(OC)=C2)C3=CC=NC=C13
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Chemical Name2,7-Naphthyridin-1(2H)-one, 4-[4-[(dimethylamino)methyl]-3,5-dimethoxyphenyl]-2-methyl-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Martin LJ, et al. J Med Chem. 2016 May 26;59(10):4462-75.
molnova catalog
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